What is the inflammation of the skin? Sensitive skin is often the result of an internal inflammatory reaction to an external trigger. These internal inflammatory reactions will be stronger in people with sensitive skin; contact with certain perfumes, cosmetics, metals or animals may for example cause itching and redness and dry out the skin. Unfortunately, this is often a hereditary problem, but it can be alleviated from the inside with antioxidants, the effects of which will be visible on the outside.